Intestinal macrophages modulate synucleinopathy along the gut–brain axis
ME-Macs as early cellular initiators of αS pathology along the gut–brain axis. Understanding these mechanism…
ME-Macs as early cellular initiators of αS pathology along the gut–brain axis. Understanding these mechanism…
muLECs and BAMs share functional analogies but are not homologous, providing an example of convergent evolutio…
A cell-intrinsic, tissue-agnostic pathway that drives differentiation of monocyte-derived macrophages into RTM…
Obesity increased SAMHD1 phosphorylation and thereby compromised its deoxynucleoside triphosphatase function, …
The indispensable role of ARPC5-containing, but not ARPC5L-containing, Arp2/3 complexes in mononuclear phagocy…
Macrophages are key for MR1 antigen presentation and MAIT cell immunity.…
Highlights•MiTEs are novel myeloid-targeted immunocytokine prodrugs for cancer immunotherapy•TREM2 antagonis…
PU.1 expression in microglia is regulated not only genetically but also epigenetically by the microenvironment…
Capillary-associated macrophages (CAMs) are selectively lost over time, contributing to impaired vascular repa…
Efferocytosis-associated reprogramming of the islet macrophages and the subsequent influence on the adaptive i…
A targetable epigenetic node of myeloid progenitor dysregulation that sustains immunoregulatory mo-macs in the…
Highlights•Astrocyte processes reduce contact with synapses before synapse removal by microglia•Microglia-de…
Highlights•Erythroblast island (EBI) macrophages are recruited to the bone metastatic niche•EBI macrophages …
A novel mode of bidirectional microglia-neuron communication centred around GM2 ganglioside turnover, identify…
Macrophages sense deviation in intracellular pH as a mechanism to guide the control of inflammatory responses.…
Healthy tissue may be damaged by the activity of immune cells working to eradicate infection. Hoagland et al. …
AbstractAs tissue resident macrophages of the central nervous system (CNS) parenchyma, microglia perform diver…
